Introduction
Today I will talk about the role of radiation therapy in treatment of cancer also the pros and cons of such modality.
First of all, over than fourteen million cases of cancer are diagnosed international each year; radiation therapy (RT) has the possibility to improve rates of healing three million and half people. These rating are based in the reality that almost fifty percent of cancer patients can benefit of RT in the manages their disease, almost half present early enough to follow curative intent.
Because radiation influence healthy tissue and tumor, obtain an agreeable curative rate, known as the chance of tumor monitoring versus the chance of inadmissible poisoning, requires the radiation dose be delivered within very tightly controlled tolerances with minimum five percent aberration.
RT kills cancer cells by damaging their DNA, it can in two ways:
The first one with damage DNA directly, the second with free radicals.
After that, these cells cannot divide and die.
Uses of radiation therapy:
RT is major element of curing cancers like breast, prostate, cervix, head and neck, lung, and brain, as well as sarcomas.
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This approach resulted on use of large radiotherapy fields that confirmed coverage the tumor, also resulted on determine toxicity. With computerized tomography (CT) scanners and computerized treatment planning, fields shaped (3D conformal radiation therapy, 3D CRT) to match tumors; the use of small fields resulted on low toxicity and chance to escalate the radiation dose, with resulting improved outcomes and lower toxicity. Now 3D CRT is the standard approach in many