Surgical Wound

ABSTRACT Wound is a breach in the skin and the exposure of subcutaneous tissue following loss of skin integrity. Post-operative wound infections are major global problem in the field of surgery leading to many complications, increased morbidity and mortality. A total 75 pus samples were collected from post-operative wound infections of which 63/75 (84%) bacterial isolates were obtained. Among the isolates, 29/63 (46%) were Gram positive and 34/63 (54%) were Gram negative organisms. The percentage prevalence of the bacterial isolates was as follows- Staphylococcus aureus 18/63 (29%), Pseudomonas aeruginosa 14/63 (22%), Coagulase negative staphylococci (CoNS) 11/63 (17%), Klebsiella pneumoniae 8/63 (13%), Proteus vulgaris 7/63 (11%) and

The risk of developing a surgical wound infection is largely determined by three factors: the load, type of microbial contamination of the wound and host susceptibility7. Cleansing is a vital component of wound management. Iodine is a highly effective topical antimicrobial that has been used clinically in the treatment of wounds for more than 170 years. It has a broad spectrum of antimicrobial activity with efficacy against bacteria, mycobacteria, fungi, protozoa and viruses and can be used to treat both acute and chronic wounds8. Therefore, the present study was taken up to screen for the presence of aerobic bacteria from post-operative wounds, to detect antibiotic susceptibility pattern and to evaluate the antibacterial activity of

MIC of PVP-I ranged between 1:4 to 1:64. The MIC of the staphylococcal isolates ranged between 1:4 to 1:32. The following was the MIC observed among the gram negative organisms- 1:2 to 1:16 for Pseudomonas aeruginosa, 1:4 to 1:32 for E.coli, 1:8 to 1:32 for Klebsiella pneumoniae and 1:4 to 1:64 for Proteus vulgaris.

DISCUSSION Post-operative wound infections have been found to pose a major problem in the field of surgery for a long time. The surveillance of nosocomial infections with an emphasis on antimicrobial audit will reduce the risk of postoperative wound infections and mortality12. Data from the past several years show an increasing resistance for drugs that were considered as the first line of treatment for post-operative wound infections this should be replaced with newer antibiotics13. In our study, a total of 75 pus samples were collected from post-operative wound infections of which 63/75 (84%) bacterial isolates were obtained. Wound infections rate in this present study was 84%.This was found to be in consistent with gowswani,201114. However, our finding was lower than reports from South Ethiopia 92% 15 and West Ethiopia 96.3% 16. This difference in prevalence of post-operative infection may be due to variation in common nosocomial pathogens inhabitant, difference in policy of infection control and prevention between countries and