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Case Study: The Pico Question In Muhlestein's Study

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1. The PICO question in Muhlestein’s study. P: Men and women who are more than 50 years old and 55 years old respectively with at least three years history of DM or men and women who are more than 40 years old and 45 years old respectively with at least 5 years history of DM and who has used anti diabetic medication for at least one year. I: Coronary computed tomography angiography (CCTA) C : Unscreened population. O : Composite of all cause mortality, non-fatal MI ,hospitalization for unstable angina and Ischemic major adverse cardiovascular events (composite of CAD death, nonfatal MI, or Unstable angina). …show more content…

2. The PICO question in McEvoy’s study. P : Asymptomatic patients from a health-screening program from south korea. I: Coronary computed tomography angiography (CCTA) for coronary atherosclerosis. C: Unscreened population. O: Medication use (Statin, aspirin, antihypertensive and oral hypoglycemic agents), secondary test referrals, revascularizations, and cardiovascular events. Q: In asymptomatic patients, does screening with CCTA for coronary atherosclerosis compared to unscreened population reduce Medication use (Statin, aspirin, antihypertensive and oral hypoglycemic agents), secondary test referrals, revascularizations, and Cardiovascular events? 3. The PICO question in on the case we discussed in class. P: Asymptomatic south asian male

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