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Pros And Cons Of Silico Testing

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Every year at least 115 million harmless animals are used in experiments worldwide. These innocent animals consist of; mice, rats, frogs, dogs, cats, rabbits, hamsters, guinea pigs, monkeys, fish, and birds. 95% of them are not protected legally by Animal Welfare Association (AWA). Animal testing is inhumane and unreliable. It has caused over one hundred million deaths and mis treatments, here alone in the United States. Yet, there are other alternatives that now exist and can replace the need for animals such as in vitro testing, in silico models, and human volunteers. Scientists now do not have an excuse to harm any of these creatures.(Peta)
Animal research and experimentation has been practiced since at least 500 BC. The ‘modern’ era of …show more content…

Researchers have developed a wide range of advanced computer models that simulate human biology and the progression of developing diseases.In silico models are typically used for testing tolerance of cosmetic substances without using innocent animals as well as predicting how drugs interact with the body with pathogens. In vitro is a way better choice when it comes to cosmetic testing. Cosmetics test on animals can include skin and eye irritation tests where chemicals are rubbed on shaved skin or dripped into the eyes without any pain relief. In silico already has a very active development and has great potential. Since these methods already are used, why not use them more often in the future or now as we speak. Rather than doing harm to the creatures that surround us, scientist who still use them as their pets, should seriously consider doing these “computer testing” techniques. …show more content…

This can also be referred as “microdosing”.How exactly does it work? Scientists use the blood from human volunteers to test for the presence of fever-causing contaminants in intravenous medicines. This can actually save thousands of rabbits each year from traditional “pyrogen” tests.(Humane Society) In some cases, the volunteers are given a small portion of a drug-dose, and advanced imaging techniques are used to monitor how the drug behaves in the body. Microdosing can certainly replace animal testing, by a long shot Although it may sound “unsafe” to some people, modern techniques allow the human brain to be safely studied down to the level of a single neuron and help researchers, without harming any of the animal’s brain. It truly is a win-win situation for both researchers and the

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This methods enables human volunteers to participate in research. It can provide information on the safety of a drug. Volunteers are given a small one-time dose of a drug that 's high enough to cause a cellular effect but low enough to affect the body. They use sophisticated imaging to monitor how the drug behaves in the body. With microdosing benefits include being able to safety test on humans and get more accurate results.

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(https://animal-testing.procon.org) Animal testing is cruel and inhumane. Animals used in experiments are commonly subjected to force feeding, forced inhalation, food and water deprivation, prolonged periods of physical restraint, the infliction of burns and other wounds to study the healing process, the infliction of pain to study its effects and remedies, and “killing by carbon dioxide asphyxiation, neck breaking, decapitation, or other means” The Draize eye test, used by cosmetics companies to evaluate irritation caused by shampoos and other products, involves rabbits being incapacitated in stocks with their eyelids held open by clips, sometimes for multiple says, so they cannot blink away the products being tested. (https://www.peta.org/issues/animals-used-for-experimentation/alternatives-animal-testing/) A method called “microdosing” can provide vital information on the safety of an experiment drug and how it is metabolized in humans prior to large-scale human trials.

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There are over 26 million animals being used for scientific and commercial testing each year in the United States. Animals are being used for developing medical treatments, checking the safety of a product, and seeing the toxicity of medication before human use. Animal testing has contributed to many life saving medications, however animal testing is inhumane and cruel. Animals used in testing are put in experiments where there is force feeding, food and water deprivation, the infliction of wounds, physical restraint, decapitation, and many other inhumane acts. Alternative testing methods now exist that can replace the use of animals being used for scientific and commercial testing.

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Another article called “Should Animals Be Used for Scientific or Commercial Testing” states that, “Artificial human skin, such as the commercially available products EpiDerm and ThinCert… can produce more useful results than testing chemicals on animal skin…computer models can predict the toxicity of substances without invasive experiments on animals” (Scientific or Commercial

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Organs on chips was created by Harvard’s Wyes Institute, which contain human cells grown in a state of the art system to mimic the structure and function of human organs and organs systems (Alternatives to Animal Testing). The chips were designed to replace the need for animals in disease research, drug testing, and toxic chemical tests (Alternatives to Animal Testing). Organs to chips have proven to be successful, in that they react more accurately than inhumane animal experiments (Alternatives to Animal Testing). MatTek’s EpiDerm™ is a three dimensional human cell derived skin model, that replicates key traits of normal human skin (Alternatives to Animal Testing). Cell based test such as this one, can be used to evaluate the safety of drugs, chemicals, cosmetics, and consumer products (Alternatives to Animal Testing).

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One of the main arguments used by activists are that results from animal testing is not successful in clinical trials with humans. While it is physically impossible to replicate a human organ or disease with an animal, you can get an extremely good representation. This will get you accurate results that will provide much more success to the testing compared to something that isn’t a close depiction – like a computer. Animal research continuing shows that even though the price is extremely high, there is no “replacement” method that comes close to the precision from use of animals. The second fact is that animal research alternatives MUST be used whenever possible.

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Animal testing is not the most reliable way to determine if a drug is safe for human use. A study done by the U.S Food and Drug Administration showed that ninety two percent of drugs entering clinical trials fail to be approved (Capaldo, Theodora). Animal testing is also very expensive and by figuring out new ways to test drugs and products we can save millions of animals and dollars. We are now able to create computer models and simulations of human organs and the researches are able to predict the way new drugs will react in the human body (“Alternatives to Animal Testing”) Other alternatives include cell cultures, micro dosing, and even donated human tissue.

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Have you ever wondered how the world comes up with the newest beauty product or the cure to the latest disease? These are found through experimenting on living creatures for multitudes of time. This animal testing is unacceptable because it’s unnecessary, unethical and unscientific. It’s unnecessary to test because what works on them does not work on humans.

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Millions upon millions of animals are killed mercilessly every year due to these experiments. “Most animal experiments are not relevant to human health, they do not contribute meaningfully to medical advances and many are undertaken simply out of curiosity and do not even pretend to hold promise for curing illnesses” (Animal). Not only does this testing waste animal lives, but humans as well. Because animal testing is so ineffective, many humans have contracted illness, irritations, mental problems, etc. because of these drugs being successful on animals and not humans.

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Therefore, even the most powerful supercomputers are unable to accurately simulate the workings of complex organs such as the brain. Computer testing relies on accurate information from animal testing, so how can you rule out animal testing entirely? There are other alternative tests like EpiDerm, but these tests still require animal testing to be accurate, without animal testing you would be unable to create safe products and treatments, possibly harming

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“More than 100 million animals are poisoned, burned, crippled, and abused in other ways in U.S. labs each year” (“Top Five Shocking”). Animal testing has become a deeply divided subject, with strong justification supporting each side. The debate regarding the ethics of this controversial practice is ongoing. Supporters of animal experimentation argue the viewpoint in which it must continue because of the enormous scientific research that animal models provide. Others, however, insist that all animal experimentation should come to an end.

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There are different alternatives to get an accurate results by not using animals for testing. Animals are tested for advancement of medicine however, that is not just the case. Animals are being used to test

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Even though the medical world is constantly making critical advancements with animal testing, new alternative methods are available that can replace animal experimentation. Different ways of experimenting are now available that substitute the use of animals. According to the article “Should Animals Be Used for Scientific or Commercial Testing?” , examples include petri dish testing, which is studying human cell samples, and microdosing, which is testing on humans with microscopic doses (animal-testing.procon.org). Petri dish testing and microdosing eliminates the use of animals by testing directly on humans without being harmful.

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Animal testing is defined as “the use of non-human animals in research and development projects, especially for purposes of determining the safety of substances such as foods or drugs” (Dictionary.com). This experimentation has been practiced since around 500 BCE, and has allowed the human race to discover many things that otherwise would have not been discovered (ProCon). The use of animal testing has increased, due to its many necessary benefits, such as: helping form vaccinations and uncovering new diseases in the specific species being tested on (AALAS). However, many animal activist groups such as, People for the Ethical Treatment of Animals (PETA), have spoken out against the issue. These groups claim animal testing to be “inhumane”

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1215 Words | 5 Pages

All things considered, animals should not be used for scientific testing because when they are tested most of the results are

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